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Andarine (S4) — research, mechanism and safety profile
Andarine (S4, GTx-007) in research: SARM mechanism, preclinical rodent data, the vision profile (xanthopsia) and WADA S1 status. Research-reagent profile (RUO).
Autor: Bartosz Bartczak
Physiotherapist with 20 years of clinical experience, graduate of Poznan University of Medical Sciences. Founder of One Peptides and lead author of clinical-perspective content.
LGD-4033 vs ostarine (MK-2866) — what the research says
LGD-4033 vs ostarine (MK-2866) — a scientific comparison of two SARMs: research phase, models, tissue selectivity and safety signals. Research reagents (RUO).
LGD-4033 (Ligandrol) — research, mechanism and safety profile (SARM)
LGD-4033 (Ligandrol): SARM mechanism, phase I data in healthy volunteers, safety signals (testosterone suppression, a DILI case report) and WADA S1 status. Research reagent (RUO).
Hallmarks of ageing — the cellular hallmarks of ageing and senescence
This material is intended for educational purposes only and describes the current state of knowledge in cell biology. It does not constitute medical advice, a diagnosis, or a recommendation to use any substances. The research compounds discussed remain the subject of scientific investigation. The hallmarks of ageing are a set of recurring cellular and molecular […]
Mitochondria and ageing — mitochondrial dysfunction and longevity in the light of research
This article is for educational purposes only and presents the state of scientific knowledge on mitochondrial biology and the processes of ageing. It does not constitute medical advice or a recommendation to use any substances. The compounds mentioned are described as objects of research, not as products for human use. Mitochondria are organelles that generate […]
Mechanisms of ageing — what science has established about why we age
The ageing of an organism is a progressive, multi-level accumulation of molecular and cellular damage that leads to a gradual loss of tissue function. Contemporary biology organises this process within the framework of the hallmarks of ageing — a set of mechanisms describing why and how we age. This guide presents these mechanisms in a […]
Sirtuins, Autophagy and mTOR — Molecular Longevity Pathways in the Light of Research
This article is educational in nature and constitutes a review of the scientific literature on the molecular pathways studied in the biology of cellular ageing. It describes mechanisms at the level of enzymes, proteins and genes — it does not constitute medical or nutritional advice and does not contain any protocol, diet or instructions for […]
Telomeres and ageing — telomere shortening and biological age in light of research
This article is educational in nature and constitutes a review of the published scientific literature on telomere biology and biomarkers of cellular ageing. It describes molecular mechanisms and the state of research, rather than use in humans. The text does not constitute medical or diagnostic advice. Some of the tools discussed (telomere length tests, epigenetic […]
NAD+ and ageing — the age-related decline of the coenzyme in light of research
This article is educational in nature and constitutes a review of the published scientific literature. A substantial part of the data cited comes from animal models or in vitro conditions; observations in humans are limited and, where they occur, this fact is clearly indicated. The text describes biochemical mechanisms and the state of research; it […]
MOTS-c — a mitochondrial-derived peptide in metabolism research
MOTS-c (Mitochondrial ORF of the Twelve S rRNA type-c) is a mitochondrial-derived peptide composed of 16 amino acids, encoded not in the cell nucleus but in mitochondrial DNA. It belongs to the class of mitochondrial-derived peptides (MDPs) and is studied as a regulator of metabolism acting through the AMPK axis. It is one of the […]
