{"id":1018,"date":"2024-11-23T08:19:02","date_gmt":"2024-11-23T08:19:02","guid":{"rendered":"https:\/\/one-peptides.com\/product\/kisspeptin-10-5mg\/"},"modified":"2026-09-29T17:04:06","modified_gmt":"2026-09-29T17:04:06","slug":"kisspeptin-10-5mg","status":"publish","type":"product","link":"https:\/\/one-peptides.com\/de\/produkt\/kisspeptin-10-5mg\/","title":{"rendered":"KISSPEPTIN-10 5MG"},"content":{"rendered":"<h2><strong>One Peptides Kisspeptin-10 5 mg &#8211; chemical reagent for laboratory tests<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Kisspeptin &#8211; Research Use Only (RUO). Chemical reagent intended only for laboratory tests. It is not intended for human consumption or diagnostic purposes.<\/span><br \/>\n<strong>Related categories and reagents:<\/strong> In the context of this area of \u200b\u200bresearch, it is also worth comparing <a href=\"https:\/\/one-peptides.com\/product\/oxytocin-10mg\/\">Oxytocin 10 mg.<\/a><\/p>\n<p><strong>Kisspeptin-10 vs oxytocin.<\/strong> Both are short peptides described in the context of neuroendocrinology, but they enter two different receptor systems. Kisspeptin-10 (1,302.45 g\/mol) is a decapeptide and a ligand of the KISS1R receptor (formerly GPR54), described in the literature in the context of regulating the hypothalamic-pituitary-gonadal axis. Oxytocin (1,007.19 g\/mol) is a cyclic nonapeptide and a ligand of OXTR, which belongs to a completely different receptor family. The research area is shared, not the mechanism; these are not interchangeable reagents.<\/p>\n<h2><strong>Introduction and research framework<\/strong><\/h2>\n<p>Kisspeptin-10 (Kp-10), also known as metastin 45-54, is a synthetic decapeptide that is the C-terminal fragment of full-molecule kisspeptin-54. This peptide is a biologically active fragment of the KISS1 gene product, which plays a central role in the regulation of the hypothalamic-pituitary-gonadal (HPG) axis by activating the KISS1R receptor (GPR54).<\/p>\n<p>The discovery of kisspeptin in 2003 was a breakthrough in understanding the mechanisms of reproductive function control at the neuroendocrine level. Kisspeptin-10 retains the full biological activity of full-molecule kisspeptin, which makes it a valuable tool in research on the regulation of gonadotropin secretion.<\/p>\n<h2><strong>General characteristics of the compound<\/strong><\/h2>\n<p>Kisspeptin-10 is a decapeptide with the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2, corresponding to positions 112-121 (or 45-54 counting from the C-terminus) of the kisspeptin precursor. This is the minimal sequence that retains full affinity for the KISS1R receptor and biological activity.<\/p>\n<p>In scientific research, Kisspeptin-10 serves as:<\/p>\n<ul>\n<li>A tool for examining the function of the KISS1R receptor<\/li>\n<li>Model in research on the HPG axis<\/li>\n<li>Reference ligand in neuroendocrine research<\/li>\n<li>Standard in kisspeptin structure-activity studies<\/li>\n<\/ul>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-1150 size-large\" src=\"https:\/\/one-peptides.com\/wp-content\/uploads\/2025\/07\/Kisspeptin-Camera-e1751211025586-1024x722.png\" alt=\"Kisspeptin-10 research peptide \/ HPG axis\" width=\"800\" height=\"564\" \/><\/p>\n<h2><strong>What is Kisspeptin-10?<\/strong><\/h2>\n<p>Kisspeptin-10 is a C-terminal decapeptide that is the active fragment of kisspeptin-54 (metastin). The KISS1 gene encodes a 145 amino acid precursor that is proteolytically processed into active forms: kisspeptin-54, -14, -13 and -10.<\/p>\n<h3><strong>History of Discovery<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>Year<\/th>\n<th>Event<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>1996<\/td>\n<td>Discovery of the KISS1 gene as a metastasis suppressor<\/td>\n<\/tr>\n<tr>\n<td>2001<\/td>\n<td>Identification of the GPR54 receptor (KISS1R)<\/td>\n<\/tr>\n<tr>\n<td>2003<\/td>\n<td>Discovery of the role of kisspeptin in GnRH regulation<\/td>\n<\/tr>\n<tr>\n<td>2003<\/td>\n<td>Association of KISS1R mutations with hypogonadism<\/td>\n<\/tr>\n<tr>\n<td>2005+<\/td>\n<td>Intensive research on reproductive functions<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>Origin of the Name<\/strong><\/h3>\n<p>The name &#8220;kisspeptin&#8221; comes from the place where the KISS1 gene was discovered &#8211; Hershey in Pennsylvania (USA), known for the production of Hershey&#8217;s Kisses chocolates. The alternative name &#8220;metastin&#8221; refers to initial research into its role in suppressing cancer metastases.<\/p>\n<h3><strong>Kisspeptin forms<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>Form<\/th>\n<th>Length<\/th>\n<th>Positions<\/th>\n<th>Activity<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Kisspeptin-54<\/td>\n<td>54 A.A<\/td>\n<td>68-121<\/td>\n<td>Full<\/td>\n<\/tr>\n<tr>\n<td>Kisspeptin-14<\/td>\n<td>14 A.A<\/td>\n<td>108-121<\/td>\n<td>Full<\/td>\n<\/tr>\n<tr>\n<td>Kisspeptin-13<\/td>\n<td>13 A.A<\/td>\n<td>109-121<\/td>\n<td>Full<\/td>\n<\/tr>\n<tr>\n<td>Kisspeptin-10<\/td>\n<td>10 A.A<\/td>\n<td>112-121<\/td>\n<td>Full<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>Structure and physicochemical properties<\/strong><\/h2>\n<h3><strong>Amino Acid Sequence<\/strong><\/h3>\n<p>Kisspeptin-10 consists of 10 amino acids:<\/p>\n<p><strong>H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2<\/strong><\/p>\n<p>One letter code: <strong>YNWNSFGLRF-NH2<\/strong><\/p>\n<h3><strong>Characteristics of Amino Acids<\/strong><\/h3>\n<ul>\n<li><strong>Position 1 (Tyre)<\/strong> \u2013 tyrosine, aromatic, N-terminus<\/li>\n<li><strong>Position 2 (Asn)<\/strong> \u2013 asparagine, polar<\/li>\n<li><strong>Position 3 (Trp)<\/strong> \u2013 tryptophan, aromatic (key)<\/li>\n<li><strong>Position 4 (Asn)<\/strong> \u2013 asparagine, polar<\/li>\n<li><strong>Position 5 (Cheese)<\/strong> \u2013 serine, polar<\/li>\n<li><strong>Position 6 (Phe)<\/strong> \u2013 phenylalanine, aromatic<\/li>\n<li><strong>Position 7 (Gly)<\/strong> \u2013 glycine<\/li>\n<li><strong>Position 8 (Leu)<\/strong> \u2013 leucine, hydrophobic<\/li>\n<li><strong>Position 9 (Arg)<\/strong> \u2013 arginine, basic<\/li>\n<li><strong>Position 10 (Phe)<\/strong> \u2013 phenylalanine, C-terminus amidated (key)<\/li>\n<\/ul>\n<h3><strong>Physicochemical properties<\/strong><\/h3>\n<table>\n<thead>\n<tr>\n<th>Parameter<\/th>\n<th>Value<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Summary formula<\/td>\n<td>C63H83N17O14<\/td>\n<\/tr>\n<tr>\n<td>Molar mass<\/td>\n<td>1302.45 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>CAS number<\/td>\n<td>374675-21-5<\/td>\n<\/tr>\n<tr>\n<td>Number of amino acids<\/td>\n<td>10<\/td>\n<\/tr>\n<tr>\n<td>C-end<\/td>\n<td>Amidated (-NH2)<\/td>\n<\/tr>\n<tr>\n<td>Isoelectric point (pI)<\/td>\n<td>~10.0 (basic)<\/td>\n<\/tr>\n<tr>\n<td>Solubility<\/td>\n<td>Soluble in water<\/td>\n<\/tr>\n<tr>\n<td>Form<\/td>\n<td>Freeze-dried powder (white)<\/td>\n<\/tr>\n<tr>\n<td>Aromatic amino acids<\/td>\n<td>4 (Tyr, Trp, 2\u00d7Phe)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><strong>RF-amide motif<\/strong><\/h3>\n<p>Kisspeptin-10 belongs to the RF-amide peptide family, characterized by the C-terminal sequence Arg-Phe-NH2:<\/p>\n<ul>\n<li>A conserved motif in vertebrates<\/li>\n<li>Crucial for binding to the receptor<\/li>\n<li>Common feature with other RF-amide peptides (RFRP, NPFF)<\/li>\n<\/ul>\n<h2><strong>Purity, identification and quality control<\/strong><\/h2>\n<h3><strong>Product Specification ONE Kisspeptin-10 5 mg<\/strong><\/h3>\n<p><strong>Quality parameters:<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<th>Test<\/th>\n<th>Method<\/th>\n<th>Specification<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Cleanliness<\/td>\n<td>HPLC<\/td>\n<td>\u226598%<\/td>\n<\/tr>\n<tr>\n<td>Identification<\/td>\n<td>MS<\/td>\n<td>1302.45 \u00b1 0.5 Da<\/td>\n<\/tr>\n<tr>\n<td>Water content<\/td>\n<td>Karl Fischer<\/td>\n<td>\u22648%<\/td>\n<\/tr>\n<tr>\n<td>Acetate content<\/td>\n<td>Titration<\/td>\n<td>\u226412%<\/td>\n<\/tr>\n<tr>\n<td>Appearance<\/td>\n<td>Visual<\/td>\n<td>White lyophilisate<\/td>\n<\/tr>\n<tr>\n<td>Solubility<\/td>\n<td>Test<\/td>\n<td>Clear in water<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>Storage and laboratory handling<\/strong><\/h2>\n<h3><strong>Storage Conditions<\/strong><\/h3>\n<p><strong>Freeze-dried form:<\/strong><br \/>\n&#8211; Temperature: -20\u00b0C (optimal)<br \/>\n&#8211; Permissible: 2-8\u00b0C (up to 1 month)<br \/>\n&#8211; Protect from light (tryptophan!)<br \/>\n&#8211; Protect against moisture<br \/>\n&#8211; Shelf life: 24 months at -20\u00b0C<\/p>\n<p><strong>After reconstitution:<\/strong><br \/>\n&#8211; Solvent: sterile water or PBS<br \/>\n&#8211; Storage: 2-8\u00b0C in the dark<br \/>\n&#8211; Use within 7-14 days<br \/>\n&#8211; Freezing aliquots recommended<br \/>\n&#8211; Avoid repeated freezing\/thawing<\/p>\n<h3><strong>Reconstitution Instructions<\/strong><\/h3>\n<ol>\n<li>Equalize the temperature of the vial (15-20 min)<\/li>\n<li>Add sterile water slowly along the side<\/li>\n<li>Recommended concentration: 0.5-2 mg\/ml<\/li>\n<li>Mix gently by turning<\/li>\n<li>Protect the solution from light<\/li>\n<li>Store in the refrigerator or freeze<\/li>\n<\/ol>\n<h3><strong>Notes on Stability<\/strong><\/h3>\n<ul>\n<li>Tryptophan at position 3 is sensitive to UV light<\/li>\n<li>Asparagines may undergo deamidation<\/li>\n<li>Store in the dark<\/li>\n<li>Avoid long-term storage in solution<\/li>\n<\/ul>\n<h2><strong>Mechanism of action at the molecular level<\/strong><\/h2>\n<h3><strong>KISS1R receptor (GPR54)<\/strong><\/h3>\n<p>Kisspeptin-10 is an agonist of the KISS1R receptor, a Gq\/11 protein-coupled GPCR. In vitro tests analyze:<\/p>\n<p><strong>Binding characteristics:<\/strong><br \/>\n&#8211; High affinity for KISS1R<br \/>\n&#8211; EC50 in the nanomolar range<br \/>\n&#8211; Comparison with longer forms of kisspeptin<\/p>\n<p><strong>Intracellular signaling:<\/strong><br \/>\n&#8211; Activation of phospholipase C<br \/>\n&#8211; IP3 and DAG production<br \/>\n&#8211; Release of Ca2+ from the ER<br \/>\n&#8211; Activation of PKC and MAPK<\/p>\n<h3><strong>Structure-Activity Research<\/strong><\/h3>\n<p>In vitro studies have established:<\/p>\n<ul>\n<li>C-terminal Phe-NH2 necessary for activity<\/li>\n<li>Trp-3 important for affinity<\/li>\n<li>N-terminal truncation tolerated up to Kp-10<\/li>\n<li>Further shortening reduces activity<\/li>\n<\/ul>\n<h3><strong>Research on Cell Cultures<\/strong><\/h3>\n<p>Kisspeptin-10 has been tested for:<\/p>\n<ul>\n<li>GnRH-producing cells (GT1-7, GnRH neurons)<\/li>\n<li>Lines expressing KISS1R<\/li>\n<li>Gonadotropic cells of the pituitary gland<\/li>\n<li>Hypothalamic neurons<\/li>\n<\/ul>\n<h3><strong>Interactions with Other Systems<\/strong><\/h3>\n<p>In vitro studies show potential interactions with:<\/p>\n<ul>\n<li>GnRH neurons<\/li>\n<li>The opioid system<\/li>\n<li>Stress neuropeptides<\/li>\n<li>Metabolic pathways<\/li>\n<\/ul>\n<h2><strong>Applications in Scientific Research<\/strong><\/h2>\n<h3><strong>Neuroendocrinology<\/strong><\/h3>\n<ul>\n<li>HPG axis adjustment mechanisms<\/li>\n<li>Control of GnRH secretion<\/li>\n<li>Integration of metabolic and reproductive signals<\/li>\n<li>Pulsatility of gonadotropin secretion<\/li>\n<\/ul>\n<h3><strong>Receptor Research<\/strong><\/h3>\n<ul>\n<li>KISS1R\/GPR54 characteristics<\/li>\n<li>Structure-activity studies of kisspeptins<\/li>\n<li>Selectivity and specificity<\/li>\n<li>Receptor desensitization<\/li>\n<\/ul>\n<h3><strong>Reproductive Biology<\/strong><\/h3>\n<ul>\n<li>Mechanisms of initiation of puberty<\/li>\n<li>Control of the sexual cycle<\/li>\n<li>Seasonality of reproduction in animals<\/li>\n<li>Photoperiodic integration<\/li>\n<\/ul>\n<h3><strong>Metabolic Research<\/strong><\/h3>\n<ul>\n<li>Connections between metabolism and reproduction<\/li>\n<li>Effect of energy state on KISS1R<\/li>\n<li>Interactions with leptin and insulin<\/li>\n<\/ul>\n<h3><strong>Reservations<\/strong><\/h3>\n<p><strong>IMPORTANT:<\/strong> The product is intended for in vitro testing only. Not intended for:<br \/>\n&#8211; Use in humans or animals<br \/>\n&#8211; Diagnostic or therapeutic purposes<br \/>\n&#8211; Any clinical use<\/p>\n<h2><strong>Summary<\/strong><\/h2>\n<p>Kisspeptin-10 is a synthetic decapeptide that is the minimal active fragment of kisspeptin, retaining full affinity for the KISS1R receptor. Its central role in regulating the HPG axis makes it an indispensable tool in neuroendocrine research and reproductive biology.<\/p>\n<p>Material One Peptides Kisspeptin-10 5 mg offers:<\/p>\n<ul>\n<li>High purity \u226598% HPLC<\/li>\n<li>Full spectrometric characterization<\/li>\n<li>Stable freeze-dried form<\/li>\n<li>Certificate of analysis for each batch<\/li>\n<\/ul>\n<h2><strong>Science FAQ<\/strong><\/h2>\n<h3><strong>1. What is Kisspeptin-10 and what is its structure?<\/strong><\/h3>\n<p>Kisspeptin-10 (Kp-10) is a synthetic decapeptide with the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2) and a molar mass of 1302.45 g\/mol. This is the C-terminal fragment of kisspeptin-54, retaining full activity towards the KISS1R receptor. The CAS number is 374675-21-5.<\/p>\n<h3><strong>2. What is the role of kisspeptin in the body?<\/strong><\/h3>\n<p>Kisspeptin is a key regulator of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin neurons in the hypothalamus control the secretion of GnRH, which in turn regulates the secretion of gonadotropins (LH, FSH) from the pituitary. Mutations in the KISS1 or KISS1R gene lead to puberty disorders.<\/p>\n<h3><strong>3. How to store Kisspeptin-10?<\/strong><\/h3>\n<p>In lyophilized form, the peptide is stored at -20\u00b0C, protected from light (due to tryptophan) and moisture. After reconstitution in sterile water, the solution is stored at 2-8\u00b0C for up to 7-14 days in the dark. It is recommended to freeze small portions for longer storage.<\/p>\n<h3><strong>4. What is the RF-amide motif and why is it important?<\/strong><\/h3>\n<p>The RF-amide motif is the C-terminal Arg-Phe-NH2 (RF-NH2) sequence, characteristic of the RF-amide peptide family to which kisspeptin belongs. This motif is necessary for binding to the KISS1R receptor &#8211; its modification leads to the loss of the biological activity of the peptide.<\/p>\n<h3><strong>5. What tests is Kisspeptin-10 used for?<\/strong><\/h3>\n<p>Kisspeptin-10 is used in in vitro studies in the field of: neuroendocrinology (regulation of the HPG axis), reproductive biology, KISS1R receptor studies, GnRH control mechanisms and integration of metabolic and reproductive signals. It is not intended for use on humans or animals.<\/p>\n<h2><strong>The most important research conclusions<\/strong><\/h2>\n<p><strong>The most important features of the ONE Kisspeptin-10 5 mg product:<\/strong><\/p>\n<ul>\n<li><strong>Type<\/strong> \u2013 neuropeptide, regulator of the HPG axis<\/li>\n<li><strong>Sequence<\/strong> \u2013 YNWNSFGLRF-NH2 (10AA)<\/li>\n<li><strong>Molar mass<\/strong> \u2013 1302.45 g\/mol<\/li>\n<li><strong>CAS number<\/strong> \u2013 374675-21-5<\/li>\n<li><strong>Receptor<\/strong> \u2013 KISS1R (GPR54)<\/li>\n<li><strong>Family<\/strong> \u2013 RF-amide peptides<\/li>\n<li><strong>Cleanliness<\/strong> \u2013 minimum 98% HPLC<\/li>\n<li><strong>Form<\/strong> \u2013 lyophilisate (white powder)<\/li>\n<li><strong>Destiny<\/strong> \u2013 only in vitro tests<\/li>\n<\/ul>\n<section class=\"scientific-references\">\n<h3>Bibliography<\/h3>\n<ol>\n<li><strong>de Roux N, et al. (2003)<\/strong> &#8220;Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54&#8221; &#8211; Proceedings of the National Academy of Sciences USA, 100(19):10972-10976.<br \/>\nLink: https:\/\/pubmed.ncbi.nlm.nih.gov\/12944565\/<\/li>\n<li><strong>Seminara SB, et al. (2003)<\/strong> &#8220;The GPR54 gene as a regulator of puberty&#8221; &#8211; New England Journal of Medicine, 349(17):1614-1627.<br \/>\nLink: https:\/\/pubmed.ncbi.nlm.nih.gov\/14573733\/<\/li>\n<li><strong>Kotani M, et al. (2001)<\/strong> &#8220;The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54&#8221; &#8211; Journal of Biological Chemistry, 276(37):34631-34636.<br \/>\nLink: https:\/\/pubmed.ncbi.nlm.nih.gov\/11457843\/<\/li>\n<\/ol>\n<\/section>\n<section class=\"scientific-references\">\n<h3>Chemical data source<\/h3>\n<ul>\n<li>PubChem. <a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/25240297\" target=\"_blank\" rel=\"noopener noreferrer\"><cite>Kisspeptin-10, CID 25240297<\/cite><\/a>.<\/li>\n<\/ul>\n<\/section>\n<p><script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Kisspeptin-10 and what is its structure?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Kisspeptin-10 (Kp-10) is a synthetic decapeptide with the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2) and a molar mass of 1302.45 g\/mol. This is the C-terminal fragment of kisspeptin-54, retaining full activity towards the KISS1R receptor. The CAS number is 374675-21-5.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the role of kisspeptin in the body?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Kisspeptin is a key regulator of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin neurons in the hypothalamus control the secretion of GnRH, which in turn regulates the secretion of gonadotropins (LH, FSH) from the pituitary. Mutations in the KISS1 or KISS1R gene lead to puberty disorders.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How to store Kisspeptin-10?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"In lyophilized form, the peptide is stored at -20\u00b0C, protected from light (due to tryptophan) and moisture. After reconstitution in sterile water, the solution is stored at 2-8\u00b0C for up to 7-14 days in the dark. It is recommended to freeze small portions for longer storage.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the RF-amide motif and why is it important?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"The RF-amide motif is the C-terminal Arg-Phe-NH2 (RF-NH2) sequence, characteristic of the RF-amide peptide family to which kisspeptin belongs. This motif is necessary for binding to the KISS1R receptor - its modification leads to the loss of the biological activity of the peptide.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What tests is Kisspeptin-10 used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Kisspeptin-10 is used in in vitro studies in the field of: neuroendocrinology (regulation of the HPG axis), reproductive biology, KISS1R receptor studies, GnRH control mechanisms and integration of metabolic and reproductive signals. It is not intended for use on humans or animals.\"\n      }\n    }\n  ]\n}\n<\/script><\/p>\n<p><!-- onep-product-reviewer-banner:start --><\/p>\n<div class=\"author-box onep-product-reviewer-banner\" style=\"border-left: 4px solid #958e09; background: #f9fafb; padding: 16px 20px; margin: 32px 0; border-radius: 4px;\">\n<p style=\"margin: 0 0 8px 0; font-size: 14px; line-height: 1.5;\"><strong>Pharmacological review:<\/strong> <a href=\"https:\/\/one-peptides.com\/team-aneta-kropicka\/\">MPharm Aneta Kropicka<\/a><br \/>\n<em>Pharmaceutical reviewer and sports supplementation expert.<\/em><br \/>\nMaster of Pharmacy with 12 years of professional experience, graduate of the Medical University of \u0141\u00f3d\u017a (2014). Verifies One Peptides product content for pharmacology, clinical dosing, and regulatory compliance across RUO \/ dietary supplement \/ drug frameworks.<\/p>\n<p style=\"margin: 0; font-size: 12px; color: #6b7280;\"><small>Published: <time datetime=\"2024-11-23\">2024-11-23<\/time> \u2022 Last updated: <time datetime=\"2026-07-09\">2026-07-09<\/time><\/small><\/p>\n<\/div>\n<p><!-- onep-product-reviewer-banner:end --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>One Peptides Kisspeptin-10 5 mg. Research Use Only (RUO). Laboratory reagent. Kisspeptin-10 (Kp-10), also known as metastin 45-54, is a synthetic decapeptide that is the C-terminal fragment of full-molecule kisspeptin-54.<\/p>","protected":false},"featured_media":1125,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_members_access_role":[],"_members_access_error":""},"product_brand":[],"product_cat":[89,34],"product_tag":[],"class_list":["post-1018","product","type-product","status-publish","has-post-thumbnail","product_cat-kisspeptin","product_cat-peptides","first","instock","sale","shipping-taxable","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 5.0.3 - aioseo.com -->\n\t<meta name=\"description\" content=\"KISSPEPTIN-10 5 mg is a RUO chemical reagent for laboratory tests. 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